MATINEE: A study looking at the microbiome (community of bacteria) in the gut and oral cavity of healthy people

Upcoming study
Expected to open July 2023
This study is currently recruiting
Expected to close April 2025
This study is closed
This study closed in April 2025
We will update this page with study results when available.
Information on study results are included below
This study closed in April 2025
Ask your healthcare team about taking part in research

What next?

Original listing:

What next?

Original listing:

About this study

There are trillions of microbes, such as bacteria, fungi and viruses that live naturally on our bodies and inside us. This is known as our microbiome. It is thought that people with interstitial lung disease (ILD) have a microbiome that is different to those who are healthy.

This study aims to assess the microbiome of the gut and oral cavity in healthy individuals, so that any differences between people with ILD can be found. This may help researchers to identify potential screening tests that could allow for earlier diagnosis, or potential targets for treatments.


What is involved?

You will be asked to provide oral swab samples and stool samples at the start of the study and then again 3 and 12 months later. You will be sent the sample collection kits in the post with a stamped return package, so you won't be required to attend the hospital to take part. The samples will be looked at to see the types of bacteria that are present. At each stage of collecting the samples, you will be sent an online questionnaire that also includes collecting information about what you have eaten recently. You will also be asked about your medical history.

You will be offered £25 per study assessment.

Summary of involvement

Sample collection kits sent in the post

Stool samples and oral swab samples at the start of the study, 3 months and 12 months

Questionnaires at time of the sample collection

Can I take part?

You may be able to take part if you are between the age of 18 and 99 year, without a history of respiratory disease.

In research studies, there are lots of different reasons why you may or may not be able to take part. These are known as inclusion and exclusion criteria (see list below). Only the research team will be able to fully determine whether you are able to take part in the study. You can withdraw at any point.

If you are not able to take part in this research study, there may be other opportunities for you to take part in different studies.

To find our more about other research opportunities visit our research finder main page.

You may be able to join this study if all of these apply:

Aged 18-99 years

No previous history of respiratory disease

Both smokers and non-smokers can take part

You will not be able to join the study of any of the following applies:

Diagnosis or history of respiratory disease

What difference could taking part make?

Taking part in this study will help researchers to understand if there are differences between the microbiomes of healthy people and people with ILD.

Where does the study take place?

Study locations

Royal Brompton Hospital

How to take part

People who would like to find out more about taking part in this study can email to express interest.

Further information

This page is a summary which provides information about an opportunity to participate in research. More detailed information about the study can be found via the following the links and through contacting the research team.

If you have any questions about this research study, please speak to your medical team.

This study is supported by

Action for Pulmonary Fibrosis
Imperial College London
Study ID number:
IRAS ID: 322270

APF does not endorse or recommend any specific study. All responsibility for the study remains with the sponsors and investigators.

Every effort is made to keep these details up to date. If you are aware of any inaccuracies, please email